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Product Manual

 

 

PRODUCT NAME

 

CATEGORY

 

MECHANISM OF ACTION

 

INDICATIONS

 

DOSAGE

 

USE IN PREGNANCY

 

USE IN CHILDREN

ACNO-T

 

Anti-acne (Retinoids)

 

It decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation, stimulates mitotic activity and increased turnover of follicular epithelial cells causing expulsion of the comedones.

 

Acne and for improving wrinkles.

 

Once daily at nighttime

 

Pregnancy Category C

 

Not Recommended

ALLYFIN

 

Antifungal

 

Inhibits biosynthesis of the ergosterol component of fungal cell membranes.

 

Interdigital tinea pedis (athlete's foot); tinea corporis (ringworm); tinea cruris (jock itch); tinea (pityriasis) versicolor caused by susceptible organisms.

 

Once or twice daily

 

Pregnancy Category B

 

Not Recommended

ANOFER

 

Haematinic 

 

In the preparation, Iron is present as Iron Polymaltose Complex, a novel iron preparation which contains non-ionic ferric iron and polymaltose in a stable complex. This facilitates a controlled absorption of the iron when it comes in contact with the mucosal cell surface.No gastric irritation and in addition, the high elemental iron content of IPC eliminates the need for frequent dosing  and therefore improves compliance. 

 

Weakness, Blood loss, General fatigue, Malaria, Menorrhagia, Pregnancy,Lactation,  Infection and worm infestation, Malnutrition, Post-operative cases

 

1-2 capsules daily 

 

Pregnancy Category C

 

Recommended

ARTICIN

 

NSAIDs

 

Inhibits prostaglandin synthesis by inhibiting cyclooxyegenase enzyme.

 

Arthritis

 

2-3 times daily

 

Pregnancy Category C (Not Recommended)

 

Not Recommended

CAREOXY

 

Vitamins and Antioxidant

 

Free radicals such as superoxide, hydroxyl ion , hydrogen peroxide and nitric oxide all contain an unpaired electron. These radicals can have negative effect on cell causing oxidative stress (oxidative damage) that leads to cell death.
Careoxy prevent cell damage by binding to the free radical and neutralizing its unpaired electron.

 

 Cardiovascular disease (To prevent atherosclerosis, Post -angioplasty
IHD inducing angina, Myocardial infarction
Post coronary artery bypass grafting)
, Respiratory disorder (Respiratory distress, Emphysema), metabolic disorder (Diabetes Mellitus), Oncology (Precancerous stages e.g. leucoplakia; Cancer of lungs, uterus, cervix etc.),Opthalmology (Cataract, Macular degeneration), Neurology (Parkinson’s disease, Alzheimer's disease,
Degenerative disorder),Rheumatology (Rheumatoid arthrits, Osteoarthritis), Dermatology (Photoaging, Radiation reaction)

 

1-2 capsules daily 

 

Pregnancy Category C

 

Recommended

CERIN

 

Disease modifying agent

 

Inhibits IL-1 synthesis and inhibit inflammatory processes and cartilage destruction .

 

Osteoarthritis, and other inflammatory arthritis

 

50 mg Twice daily

 

Pregnancy Category C

 

Not Recommended

CLINACE GEL

 

Lincosamide antibiotics

 

It inhibits protein synthesis by binding with 50S ribosomal subunits.

 

Acne vulgaris and infections caused by potentially harmful bacteria, such as Streptococcus and Staphylococcus, Methicillin-resistant Staphylococcus aureus (MRSA).

 

Once daily at nighttime

 

Category B

 

Not Recommended

COSMELITE

 

Super Potent Corticosteroids

 

It inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Inflammatory and pruritic manifestations of corticosteroid responsive dermatoses (eczema, psoriasis, seborrhea); several auto-immune diseases including alopecia areata, vitiligo and lichen planus(auto immune skin nodules).

 

Twice daily

 

Pregnancy Category C

 

Not Recommended

COSMELITE-G

 

Super Potent Corticosteroids +Antibiotic 

 

Clobetsol inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.Gentamicin inhibits protein synthesis by binding with ribosomal RNA.

 

Corticosteroid responsive dermatoses when complicated by secondary infection caused by organisms sensitive to gentamicin or when the possibility of such infection is suspected.

 

1-2 times daily

 

Pregnancy Category C

 

Not Recommended

COSMELITE-GM

 

Super Potent Corticosteroids +Antibiotic +Antifungal 

 

Clobetsol inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.Miconazole works by inhibiting the synthesis of ergosterol.Neomycin
inhibits protein synthesis by binding with ribosomal RNA.

 

Inflammatory bacterial or fungal or mixed skin infections like: Infected atopic dermatitis, infected excoriation, and bacterial superinfection of chronic superficial mycoses, otitis externa, and other infected (mixed/suspected) steroid-responsive dermatoses.

 

Twice daily 

 

Pregnancy Category C

 

Not Recommended

COSMELITE-S

 

Super Potent Corticosteriods+Keratolytic

 

Clobetasol  inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2. Salicylic acid breaks down keratin.

 

Inflammatory  manifestations of hyperkeratotic and dry corticosteroid-responsive dermatoses such as psoriasis, chronic atopic dermatitis, neurodermatitis, lichen planus, eczema, dyshidrosis, seborrheic dermatitis of the scalp,ichthyosis vulgaris and other ichthyotic conditions.

 

Once or Twice daily

 

Pregnancy Category C

 

Not Recommended

DERMACORT

 

Less Potent Corticosteroids

 

It inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Inflammatory and pruritic manifestations of corticosteroid responsive dermatoses

 

2-4 times daily

 

Pregnancy Category C

 

Recommended 

ELOZ

 

Antifungal

 

Eloz, a triazole antifungal agent  inhibits the cytochrome P450-dependent synthesis of ergosterol, which is a vital component of fungal cell membranes. This, in turn, causes fungal cell leakage and ultimately fungal cell death.

 

Oropharyngeal Candidiasis, Vulvovaginal candidiasis, pityriasis versicolor, tinea pedis, tinea cruris, tinea corporis, tinea manuum,
Onychomycosis, Systemic mycoses: aspergillosis, candidiasis, histoplasmosis and cryptococcosis (including cryptococcal meningitis).

 

1-2 times daily

 

Pregnancy Category C

 

Not Recommended

FAST RELIEF

 

Analgesic

 

Diclofenac inhibits prostaglandins synthesis by inhibiting cyclooxygenase enzyme.Menthol acts on the temperature receptors and gives sensation of coolness, constricts capillaries, and decrease  their permeability. Methyl salicylate decreases the pain because of irritation of skin receptor sand inhibition of  prostaglandins synthesis.Linseed oil  has anti-inflammatory, antioxidant actions and improves blood circulation as well.

 

Back pain; Sprain & strains; Soft tissue disorders; Osteoarthritis; Spondylosis; Cervical spondylosis; Injury Pain; Arthritis; Shoulder lesions; Frozen Shoulder; Prolapsed intervertebral disc; Thumb, and Knee Stiffness; Rheumatoid arthritis; Tennis elbow

 

3 to 4 times  daily

 

Contraindicated in last trimester of Pregnancy

 

Not Recommended

FLUTICA

 

Mild Potent Corticosteroid

 

Flutica inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2. 

 

Inflammatory and pruritic manifestations of corticosteroid responsive dermatoses

 

Twice daily

 

Pregnancy Category C

 

Recommended for  3 months and older

FLUBACT-M

 

Mild Potent Corticosteroid+Antibacterial

 

Flutica inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase

 

Inflammatory and pruritic symptoms of bacterial dermatoses, eczema and psoriasis.

 

Once daily

 

Fluticasone: C Mupirocin: B   

 

Not Recommended

FUNGITOP

 

Triazole Antifungal

 

Fungitop inhibits ergosterol(component of fungal cell membrane) formation by inhibiting enzyme 14-α-demethylase. This, in turn, causes fungal cell leakage and ultimately fungal cell death.

 

Dermatomycoses caused by dermatophytes, yeasts and molds: in particular Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor and Candida infections.

 

Once daily

 

M

 

Recommended 

FUSIMAR

 

Antibiotics

 

It inhibits bacterial protein synthesis by stabillizing the ribosome-guanosine  diphosphate elongation factor G-complex. 

 

Impetigo, whitlow (paroncychia) infection of hair folicle(sychosis). It is also used in carbuncles, boils, erthrasma, hideradenitis, eczema/dermatitis that has become infected.

 

2-3 times daily

 

Pregnancy Category C

 

Recommended

FUSIMAR H

 

Antibiotics +Corticosteroids 

 

Fusidic acid inhibits bacterial protein synthesis by stabillizing the ribosome-guanosine  diphosphate elongation factor G-complex. Hydrocortisone inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Primary irritant dermatitis, Contact allergic dermatitis, Eczema (atopic; infantile; discoid; stasis) Seborrhoeic dermatitis, Lichen simplex, pruritus ani and Flexural psoriasis.

 

2-3 times daily

 

Pregnancy Category C

 

Recommended above 1 year of age

HALOBET

 

Potent Corticosteroids

 

It inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Inflammatory and pruritic manifestations of corticosteroid responsive dermatoses

 

Once or twice daily

 

Pregnancy Category C

 

Not Recommended

HALOBET-F

 

Super Potent Corticosteroids +Antibiotic 

 

Halobetasol nhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.Fusidic Acid inhibits protein synthesis by inhibiting elongation factor G-complex and thus inhibiting protein chain elongation.

 

Corticosteroid responsive dermatoses when complicated by secondary infection caused by organisms sensitive to fusidic acid or when the possibility of such infection is suspected.

 

Twice daily

 

Pregnancy Category C

 

Not Recommended

HALOBET-G

 

Super Potent Corticosteroids +Antibiotic 

 

Halobetasol nhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.Gentamicin inhibits protein synthesis by binding with ribosomal RNA.

 

Corticosteroid responsive dermatoses when complicated by secondary infection caused by organisms sensitive to gentamicin or when the possibility of such infection is suspected.

 

1-2 times daily

 

Pregnancy Category C

 

Not Recommended

HALOBET-S

 

Super Potent Corticosteroids+ keratolytic

 

Halobetasol inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2. Salicylic acid breaks down keratin.

 

Inflammatory  manifestations of hyperkeratotic and dry corticosteroid-responsive dermatoses such as psoriasis, chronic atopic dermatitis, neurodermatitis, lichen planus, eczema, dyshidrosis, seborrheic dermatitis of the scalp,ichthyosis vulgaris and other ichthyotic conditions.

 

Once or Twice daily

 

Pregnancy Category C

 

Not Recommended

KINZOLE

 

Antifungal

 

Kinzole inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane. This causes cell leakage and finally fungal cell death.

 

Tinea infections, Pityriasis versicolor and Cutaneous Candidiasis 

 

Once daily

 

Pregnancy Category C

 

Not Recommended

LIGNO

 

local anaesthetic

 

Lignocaine is a local anaesthetic of the amide type. It produces a reversible loss of sensation by preventing or diminishing the conduction of sensory nerve impulses near the site of application.

 

Local anaesthesia and lubrication during catheterisation, exploration by sound and other endourethral operations and examinations.
Cystoscopy and symptomatic treatment of painful cystitis and urethritis.

 

 

 

Pregnancy Category B

 

Recommended

M-BACT

 

Antibiotics

 

Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase

 

Impetigo, sutured wounds, lacerations, abrasions, eczema, superficial ulcers, burns, staphylococcus-infected burns (especially those colonized with MRSA) and secnodary infections

 

Three times daily

 

Category B

 

Recommended in age groups above 3 months.

MELACARE

 

Depigmenting agent

 

Melacare act by inhibiting one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis; causing degradation of melanosomes and eventually necrosis of the whole melanocytes.

 

Hyperpigmented skin conditions such as cholasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation. 

 

Once Daily at evening

 

Pregnancy Category C

 

Not Recommended

MELACARE FORTE

 

Depigmenting agent

 

Melacare Forte act by inhibiting one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis; causing degradation of melanosomes and eventually necrosis of the whole melanocytes.

 

Hyperpigmented skin conditions such as cholasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation. 

 

Once Daily at evening

 

Pregnancy Category C

 

Not Recommended

MELABRITE

 

Depigmenting agent

 

Hydroquinone produces reversible lightening of the skin by interfering with melanin production by the melanocytes. Specifically, inhibition of the enzymatic conversion of tyrosine to DOPA (dihydroxyphenylalanine) results in the desired chemical reduction of pigment. Ultimately, this causes a decrease in the number of melanocytes and decreased transfer of melanin leading to lighter skin.

 

Hyperpigmented skin conditions such as cholasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation. 

 

Once Daily at evening

 

Pregnancy Category C

 

Not Recommended

MELACLEAN

 

Depigmenting agent

 

Melaclean act by inhibiting one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis; causing degradation of melanosomes and eventually necrosis of the whole melanocytes.

 

Hyperpigmented skin conditions such as cholasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation. 

 

Once Daily at evening

 

Pregnancy Category C

 

Not Recommended

MOMTAS

 

Mild Corticosteroids

 

It inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, such as psoriasis and atopic dermatitis.

 

Once daily

 

Pregnancy Category C

 

Recommended above 2 years of age

MUCOHEAL

 

Medium PotencyCorticosteriod

 

It inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Mouth ulcers, also known as canker sores and for the temporary relief of pain and discomfort associated with oral inflammatory lesions and ulcerative lesions resulting from trauma.

 

2-3 times daily

 

Pregnancy Category C

 

Not Recommended

NITROSTAT

 

Anorectal 

 

Nitroglycerin is converted by the body into free nitric oxide (NO), which  promote the formation of cyclic guanosine 3’,5’-monophosphate (cyclic GMP) in smooth muscle and other tissues. This leads to dephosphorylation of myosin light chains and results in vasodilatation.  

 

 Treatment of moderate to severe pain associated with chronic anal fissure.

 

1.5-2cm of ointment should be applied intra-anally every 12 hours for up to 3 weeks.

 

Pregnancy Category C

 

Not Recommended

PERIACNE

 

Antiacne

 

It works by breaking down keratin.This helps break down comedones (blackheads and whiteheads) and unblocks the sebaceous glands. It  works by introducing oxygen into the pore, thereby killing P. acnes, which can not live in aerobic(oxygen-rich) environment. 

 

Acne Vulgaris

 

2-3 times daily

 

Pregnancy Category C

 

Not Recommended

PG-LIN

 

Anticonvulsant with secondary analgesic action

 

Inhibits calcium channel in the central nervous system and inhibits the release of neurotransmitters responsible for pain and seizure.

 

Neuropathic pain, partial onset of seizures and anxiety

 

2-3 times daily

 

Pregnancy Category C

 

Not Recommended

RZOL

 

Proton pump inhibitor

 

Suppresses gastric acid secretion by blocking acid (proton) pump within gastric parietal cells.

 

For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, treatment of pathological hypersecretory conditions, including Zollinger-Ellison Syndrome

 

Once daily

 

Pregnancy Category B

 

Recommended 

SALSA

 

Keratolytic

 

It breaks down keratin.

 

SALSA is a topical aid in the removal of excessive keratin in hyperkeratotic skin disorders, including verrucae, and the various ichthyoses, keratosis palmaris and plantaris, keratosis pilaris, pityriasis rubra pilaris, and psoriasis (including body, scalp, palms and soles).

 

Once at night time

 

Pregnancy Category C

 

Not Recommended

SERZOL & SERZOL-V 

 

Imidazole Antifungal

 

Serzol inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane. This causes cell leakage and finally fungal cell death.

 

Interdigital tinea pedis, Vulvovaginal Candidiasis; Serzol-V: Vaginal Candidiasis & Mixed vaginal infections

 

SERZOL: Twice daily; SERZOL-V: Once daily

 

Pregnancy Category C

 

Not Recommended

SCARIN

 

Scabidical Agent

 

Inhibits sodium channel and paralyses arthropods

 

Scabies and infestations with pests

 

Once

 

Pregnancy Category C

 

Recommended

TERFIN CAPSULES

 

Allylamine Antifungal

 

Terfin inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane, via inhibition of squalene epoxidase enzyme. This causes cell leakage and finally fungal cell death.

 

Tinea infections, Onychomycosis, Pityriasis versicolor and Candidiasis 

 

250 mg once daily; 6 weeks for Fingernail Onychomycosis and 12 weeks for Toenail Onychomycosis

 

Pregnancy Category B

 

Not Recommended

TERFIN CREAM

 

Allylamine Antifungal

 

Terfin inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane, via inhibition of squalene epoxidase enzyme. This causes cell leakage and finally fungal cell death.

 

Tinea infections, Pityriasis versicolor and Candidiasis 

 

Once or twice daily.

 

Pregnancy Category B

 

Not Recommended

TERFIN PLUS

 

Antifungal+Corticosteriods

 

Terfin inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane, via inhibition of squalene epoxidase enzyme. This causes cell leakage and finally fungal cell death.Mometasone inhibits prostaglandins synthesis by inhibiting enzyme Phospholipase A2.

 

Swelling and inflammatory skin disorders associated with Fungal infection.

 

Once daily 

 

Terbinafine: B, Mometasone: C

 

Safety and effectiveness not established.

TOPALENE

 

Anti-acne

 

Adapalene regulates cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris. 

 

Acne Vulgaris

 

Twice daily

 

Pregnancy Category C; 

 

Not Recommended

TOPALENE CN

 

Anti-acne

 

Adapalene regulates cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris. Clindamycin inhibits bacterial protein synthesis at the ribosomal level by binding to 50S ribosomal subunit.

 

Acne Vulgaris

 

Twice daily

 

Adapalene: Pregnancy Category C; Clindamycin: Pregnancy Category B

 

Not Recommended

TRISPORIN

 

Antibiotics

 

Neomycin inhibits protein synthesis by binding with ribosomal RNA.Polymyxin B
increases the permeability of the bacterial cell membrane by interacting with the phospholipid components of the membrane.Bacitracin
interferes with bacterial cell wall synthesis by inhibition of the regeneration of phospholipid receptors involved in peptidoglycan synthesis.

 

Treating and preventing infection due to minor cuts, scrapes, and burns.

 

1 to 3 times daily

 

Pregnancy Category C

 

Recommended above 2 years of age

VIRODERM

 

Antiviral

 

The inhibitory activity of aciclovir is highly selective due to its affinity for the enzyme thymidine kinase. This viral enzyme converts Aciclovir into Aciclovir monophosphate, a nucleotide analogue. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzyme.  Aciclovir triphosphate stops replication of herpes viral DNA.

 

Herpes labialis (Cold Sores), Genital herpes and certain types of sores caused by herpes simplex virus.

 

Five times daily

 

Pregnancy Category B

 

Not Recommended